The role of CD133 in cancer: a concise review - PMC
网页2018年7月9日 · CD133 (also known as AC133 and prominin-1) is the most frequently used cell surface antigen to detect and isolate CSCs from various solid tumors , including brain, colon, pancreas, prostate, lung, and liver. There has recently been, however, some contrasting evidence of the accuracy associated with using CD133 as a marker for CSC …
PROM1：一种新的肿瘤干细胞CSCs表面标志物，未来新分子靶 …
网页该研究团队开发了靶向cd133-gsc的嵌合抗原受体巨噬细胞（car-mΦ）免疫疗法，用于清除肿瘤切除后残留的cd133-gscs。本项研究证实，在神经胶质瘤gbm小鼠模型中，靶向cd133-gscs，可发挥抗肿瘤免疫作用，抑制gbm术后的复发率，并减少抗肿瘤药物的毒副作用。
CD133 - Wikipedia
网页CD133 antigen, also known as prominin-1, is a glycoprotein that in humans is encoded by the PROM1 gene. [5] [6] It is a member of pentaspan transmembrane glycoproteins, which specifically localize to cellular protrusions.
CD133: a stem cell biomarker and beyond - PMC - National …
网页2013年7月1日 · Cancer stem cells (CSCs) or tumor initiating cells (TICs) contribute to tumorigenesis, metastasis, recurrence and chemoresistance. CD133, a pentaspan membrane glycoprotein, has been used as a stem cell biomarker for isolation of stem-like cells from a variety of normal and pathological tissues as well as cell lines since its …
CD133: beyond a cancer stem cell biomarker - PubMed
网页CD133 (prominin-1), a pentaspan membrane glycoprotein, is one of the most well-characterized biomarkers used for the isolation of cancer stem cells (CSCs). The presence of CSCs is one of the main causes of tumour reversal and resilience. Accumulating evidence has shown that CD133 might be responsible for CSCs tumourigenesis, metastasis and ...
Functional Roles of CD133: More than Stemness Associated Factor ...
网页2023年11月3日 · CD133 protein has been one of the most used surface markers to select and identify cancer cells with stem-like features. However, its expression is not restricted to tumoral cells; it is also expressed in differentiated cells and stem/progenitor cells in various normal tissues. CD133 participates in ….
CD133 (Prominin-1)的结构、功能及其相关抗体的研究进展
网页2019年5月12日 · CD133(Prominin-1)是五次跨膜糖蛋白Prominin家族的成员之一,最初作为特异性标志物用于筛选人造血干细胞和祖细胞,随后用于分离鉴定各种肿瘤干细胞的特定细胞亚群。
Functional Roles of CD133: More than Stemness Associated Factor ...
网页2023年11月3日 · CD133: Structure, Localization, and Posttranslational Modifications. CD133 (also called Prominin-1) is a pentaspan transmembrane glycoprotein widely used for stem and progenitor cell identification in several normal tissues and cancer stem-like cells of different types of cancer.
Isolation, identification and expression of specific human CD133 ...
网页2013年11月25日 · CD133, a 120 KDa glycoprotein is a transmembrane glycoprotein which has been recently used as a cancer stem cell (CSCs) marker in a variety of carcinomas. CD133 + cells possess strong ...
CD133+ endothelial-like stem cells restore neovascularization and ...
网页2023年11月9日 · Here, using lineage tracing and single-cell transcriptomics, we identify a population of CD133+ bone marrow-derived endothelial-like cells (ELCs) as potential endothelial progenitor cells, which...
- 某些结果已被删除
跳至内容