nhs.net There remains uncertainty regarding the existence, mechanism and frequency of opioid-induced hyperalgesia (OIH). Literature to date has been dominated by the phenanthrene opioids, fentanyl and ...
They further assessed mechanical hyperalgesia and spontaneous muscle pain utilizing a behavioral model. Rats were trained to lean against the experimenter's hand wearing leather gloves. Von Frey ...
It was previously reported that in 5 patients with small-fiber neuropathy, neuropathic pain, and hyperalgesia, application of a single, brief electrical stimulus to the skin could give rise to 2 ...
The neuraxial delivery of drugs has become a cornerstone in the management of pain, leveraging the pivotal roles of the dorsal root ganglion (DRG) and dorsal horn. These spinal structures are key in ...
Adrenal insufficiency. Opioid-induced hyperalgesia (OIH) and allodynia; consider dose reduction of current opioid or opioid rotation if OIH is suspected. Monitor for signs of hypotension when ...
Silverman, Richard B Candiotti, Keith A and Gitlin, Melvin C 2012. Tapentadol Extended-Release: A Recent Addition to our Analgesic Armamentarium. Pain Management, Vol ...