Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...

The intricate relationship between the dopaminergic system and olfactory associative learning in Drosophila has been an intense scientific inquiry. Leveraging the formidable genetic tools, we ...

Mice with a genetic mutation, which can also occur in humans, behave manically The risk gene adenylyl cyclase 2 is associated with bipolar disorder, as has been repeatedly confirmed in genome-wide ...

1 Institute of Molecular Virology, Centre for Molecular Biology of Inflammation, Westfaelische Wilhelms-University, Muenster, Germany 2 Institute of Pharmaceutical Technologies, Moscow, Russia ...

The risk gene adenylyl cyclase 2 is associated with bipolar disorder, as has been repeatedly confirmed in genome-wide association studies. However, until now there has not been any proof of a ...

The Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta pipeline drugs market research report outlays comprehensive information on the Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta ...

Translational regulation of inflammation was studied by quantification of immune cell infiltration, inflammatory gene expression, and cardiac function after short-term inhibition of translation ...

A new tool for monitoring immune health patterns over time reveals how a pair of checkpoint inhibitor therapies works together to recruit new cancer-fighting T cells with every infusion.

A new research paper was published in Oncotarget, titled "Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties." As stated within the paper, despite ...

Zasocitinib, a tyrosine kinase 2 (TYK2) inhibitor, at oral doses of ≥ 5 mg led to greater skin clearance than placebo over a period of 12 weeks, in a phase 2b study. Researchers performed a ...