The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated by G-protein molecules associated with the adrenergic receptor. Adenylyl cyclase creates ...

The risk gene adenylyl cyclase 2 is associated with bipolar disorder, as has been repeatedly confirmed in genome-wide association studies. However, until now there has not been any proof of a ...

Combining classical yeast genetics with molecular biology, we identified genes required for both repression and derepression of ƒbp1 transcription, including almost all of the genes of the cyclic AMP ...

Like most signaling pathways, two-component systems are modular schemes built around a central mechanism involving conserved domains. The conserved kinase core of the HK catalyzes ...

I fell in love with cable driven mechanisms a few years ago and put together some of my first mechanical tentacles to celebrate. But only after playing with them did I start to understand the ...

Defense mechanisms are rooted in Freud’s theory of personality.According to his model, the mind has three dueling forces: the id (unconscious and primitive urges for food, comfort, and sex), the ...

Molecular Psychiatry is a scientific journal published by Nature Publishing Group. It publishes papers in biological psychiatry and, e.g., about psychiatric genetics. With an impact factor of 15. ...

Two enzymes, a peptidase and a cyclase, then collaborate to convert a linear precursor peptide into the distinctive knotted lasso structure. Since their discovery over three decades ago ...

A mechanism is a set of moving parts that work together to make something happen. A slider is a kind of mechanism that has a bar or rod that moves forwards and backwards, or side to side ...

McDonough, Peter Shin, Doh C. and Moisés, José Álvaro 1998. Democratization and Participation: Comparing Spain, Brazil, and Korea. The Journal of Politics, Vol. 60 ...