The study demonstrated that individuals with CANVAS had significantly smaller nerve cross-sectional area (CSA) across various nerves. Patients with Friedreich ataxia (FA), neuropathy, and vestibular ...

The finding that high relative humidity is protective against PAH in mice studies may have important implications in future therapeutic developments. High relative humidity is protective against ...

The combination of immunoCAP assay and REMA score was particularly useful in determining the best venom immunotherapy for hymenoptera venom allergy anaphylaxis prevention. A new case report highlights ...

In the Annals of Cardiac Anaesthesia, physicians presented the case of a patient with systemic mastocytosis (SM) who was successfully managed with CytoSorb ® during cardiopulmonary bypass (CPB) for ...

In both cases presented, prophylactic use of phenylephrine prevented rapid hemodynamic changes during surgery. Two new case reports from Japan have been published in which neuraxial anesthesia was ...

The diagnosis of SM has been based on histology and morphology, along with phenotypic and molecular criteria, since 2001. Among individuals with systemic mastocytosis (SM), a lack of CD2 expression is ...

Early results from the Summit trial suggest bezuclastinib is a promising therapy for nonadvanced SM, warranting further investigation. Initial results from part 1a of the Summit trial presented at the ...

Notably, overexpression of Mfn2 effectively reverses the Warburg effect in pulmonary arterial smooth muscle cells associated with PAH. Targeting the Mitofusion 2 (Mfn2)-Warburg effect nexus in ...

Epidemiology as a discipline continues to evolve today, as evident by efforts to better classify cases of pulmonary arterial hypertension (PAH). Epidemiological studies as a discipline has undergone a ...

The US Capitol building in Washington, DC (Photo by Larry Luxner) The Rare Pediatric Disease Priority Review Voucher program allows FDA review of an application to be completed in 6 months instead of ...

CAF levels were significantly higher in patients with anti-AChR antibody positive MG compared to healthy people. Baseline and post-treatment C-terminal agrin fragment (CAF) levels inversely correlate ...

New research suggests that depressive symptoms may be associated with disease severity and cirrhosis in patients with primary biliary cholangitis (PBC).