Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...
Anisopoikilocytosis Condition in which RBCs display both sizes and shapes that are variable and abnormal Basophilic Stippling Immature RBCs display bluish flecks or punctate granules when exposed ...
It turns out that these white spots – medically known as punctate leukonychia – can be triggered by a whole host of factors, but a nutrient deficiency isn’t likely to be one of them.
This manuscript describes the impact of modulating signaling by a key regulatory enzyme, Dual Leucine Zipper Kinase (DLK), on hippocampal neurons. The results are interesting and will be important for ...