肾毒性机制：与其在肾皮质，尤其是近曲小管细胞中的积累有关。这些药物可损伤刷状缘膜的完整性，导致细胞内钙稳态失衡、线粒体功能障碍、增加氧化应激，最终引起细胞损伤和凋亡。在分子水平上，氨基糖苷类还能与细胞内的磷脂和蛋白质相互作用，干扰细胞的正常代谢活动。

Iterum Therapeutics faces a mixed reception for its therapy for uncomplicated urinary tract infections (UTIs) as experts ...

"Cystitis is a condition that starts with inflammation in the bladder and is usually caused by a urinary tract infection (UTI ...

Novakovic. Some antibiotics (such as metronidazole and nitrofurantoin), laxatives (such as cascara or senna), and other medications (such as methocarbamol and methyldopa) can also cause urine to ...

It's all too easy to overlook the colour of your urine, but a GP has now issued an urgent warning about certain shades, ...

Anyone eligible can book their vaccinations from 9am via the NHS website, by downloading the NHS App, or by calling 119 for free if they can’t get online. The vaccinations, which will be available ...

Rebecca Grant, PhD, is an infectious disease epidemiologist within the Service de prévention et contrôle de l’infection at ...